SimplexaTM EBV Kit

SimplexaTM EBV Kit

A real-time PCR assay intended for the in vitro quantitative detection of Epstein-Barr virus (EBV).

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KIT for Infectious Diseases

Overview

Background

The Epstein-Barr virus (EBV), a widespread human herpes virus with B-lymphocyte tropism, is the causative agent of infectious mononucleosis, and is strongly associated with several human malignancies. Infection with EBV is common and is generally subclinical or presents as a self-limited illness lasting 2 to 3 weeks. As a member of the herpes family, EBV can remain latent for long periods of time, and become reactivated at a later stage. Though the initial infection may result in a relatively benign syndrome, reactivation in an immunocompromised person can lead to more serious results. Monitoring of EBV viral load may help with the identification of post-transplantation lymphoproliferative disorders, and monitoring lymphomas in patients with the acquired immunodeficiency syndrome.1,2

1. Au W-Y et al, Quantification of circulating Epstein-Barr virus (EBV) DNA in the diagnosis and monitoring of natural killer cell and EBV-positive lymphomas in immunocompetent patients. Blood, 1 July 2004 _ Volume 104, Number 1; 243-249.
2. Cornelissen J, Molecular monitoring of EBV-positive lymphoma. Blood, 1 July 2004 _ Volume 104, Number 1; 9.

 

Why to choose it

A reliable and accurate assay for quantitation of Epstein-Barr virus (EBV) nucleic acids in whole blood specimens.

Benefits

SimplexaTM EBV Kit
Reliability

Reliable performance that you can count on

sensitivity of 900 copies/mL

The Simplexa™ EBV Kit has a sensitivity of 900 copies/mL and targets a well conserved region of the Lmp2A gene.

SimplexaTM EBV Kit
Sensitivity Linear range Calibration Target
Sensitivity900 copies/mL Linear range900 copies/mL to 807 million copies/mL
(2.95 log copies/mL to 8.91 log copies/mL)
CalibrationExternal five point calibration
EBV amplicon in human base matrix
TargetWell conserved region
of the Lmp2A gene

Ordering info

Product Code Reactions
Product

Simplexa™ EBV Kit

Code MOL2400 Reactions 100
Product

Simplexa™ EBV Quantitation Standards

Code MOL2410 Reactions 5 x 400 µL

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assay protocols and more.

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