Simplexa™ EBV Kit

The Epstein-Barr virus (EBV), a widespread human herpes virus with B-lymphocyte tropism, is the causative agent of infectious mononucleosis, and is strongly associated with several human malignancies. Infection with EBV is common and is generally subclinical or presents as a self-limited illness lasting 2 to 3 weeks. As a member of the herpes family, EBV can remain latent for long periods of time, and become reactivated at a later stage. Though the initial infection may result in a relatively benign syndrome, reactivation in an immunocompromised person can lead to more serious results. Monitoring of EBV viral load may help with the identification of post-transplantation lymphoproliferative disorders, and monitoring lymphomas in patients with the acquired immunodeficiency syndrome.^1,2

1. Au W-Y et al, Quantification of circulating Epstein-Barr virus (EBV) DNA in the diagnosis and monitoring of natural killer cell and EBV-positive lymphomas in immunocompetent patients. Blood, 1 July 2004 _ Volume 104, Number 1; 243-249.
2. Cornelissen J, Molecular monitoring of EBV-positive lymphoma. Blood, 1 July 2004 _ Volume 104, Number 1; 9.

A reliable and accurate assay for quantitation of Epstein-Barr virus (EBV) nucleic acids in whole blood specimens.